PRISM
=====
Version: 4.5.dev
Date: Sat Mar 14 14:33:59 UTC 2020
Hostname: e72bdd194fc5
Memory limits: cudd=4g, java(heap)=11g
Command line: prism -javamaxmem 11g -cuddmaxmem 4g -ii -heuristic speed -e 1e-6 -ddextraactionvars 100 -maxiters 1000000 mapk_cascade.prism mapk_cascade.props --property reactions -const 'N=4,T=30'
Parsing model file "mapk_cascade.prism"...
Type: CTMC
Modules: E1 E2 KPTASE KKPTASE MAPK MAPKK MAPKKK
Variables: e1 e2 kptase kkptase k k_kkpp kp kp_kkpp kp_ptase kpp kpp_ptase kk kk_kkkp kkp kkp_kkkp kkp_ptase kkpp kkpp_ptase kkk kkk_e1 kkkp kkkp_e2
Parsing properties file "mapk_cascade.props"...
3 properties:
(1) "activated_T": R{"activated"}=? [ I=T ]
(2) "activated_time": R{"time"}=? [ F kpp=N ]
(3) "reactions": R{"reactions"}=? [ C<=T ]
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Model checking: "reactions": R{"reactions"}=? [ C<=T ]
Model constants: N=4
Property constants: T=30
Warning: Switching to sparse engine and (backwards) Gauss Seidel (default for heuristic=speed).
Building model...
Model constants: N=4
Computing reachable states...
Reachability (BFS): 44 iterations in 3.46 seconds (average 0.078591, setup 0.00)
Time for model construction: 3.699 seconds.
Type: CTMC
States: 99535 (1 initial)
Transitions: 910872
Rate matrix: 111563 nodes (14 terminal), 910872 minterms, vars: 58r/58c
Computing rewards...
Engine: Sparse
Building sparse matrix... [n=99535, nnz=910872, compact] [3.6 MB]
Creating vector for diagonals... [dist=127, compact] [195.4 KB]
Allocating iteration vectors... [3 x 777.6 KB]
TOTAL: [6.0 MB]
Uniformisation: q.t = 2142.000000 x 30.000000 = 64260.000000
Fox-Glynn: left = 62483, right = 66413
Starting iterations...
Iteration 1326 (of 66413): max relative diff=0.003018, 5.00 sec so far
Iteration 2655 (of 66413): max relative diff=0.001446, 10.01 sec so far
Iteration 3981 (of 66413): max relative diff=0.000920, 15.01 sec so far
Iteration 5304 (of 66413): max relative diff=0.000654, 20.01 sec so far
Iteration 6626 (of 66413): max relative diff=0.000494, 25.02 sec so far
Iteration 7953 (of 66413): max relative diff=0.000385, 30.02 sec so far
Iteration 9280 (of 66413): max relative diff=0.000308, 35.02 sec so far
Iteration 10607 (of 66413): max relative diff=0.000251, 40.02 sec so far
Iteration 11936 (of 66413): max relative diff=0.000206, 45.03 sec so far
Iteration 13261 (of 66413): max relative diff=0.000172, 50.03 sec so far
Iteration 14585 (of 66413): max relative diff=0.000144, 55.04 sec so far
Iteration 15908 (of 66413): max relative diff=0.000121, 60.04 sec so far
Iteration 17233 (of 66413): max relative diff=0.000102, 65.04 sec so far
Iteration 18559 (of 66413): max relative diff=0.000086, 70.04 sec so far
Iteration 19879 (of 66413): max relative diff=0.000073, 75.05 sec so far
Iteration 21189 (of 66413): max relative diff=0.000062, 80.05 sec so far
Iteration 22514 (of 66413): max relative diff=0.000053, 85.05 sec so far
Iteration 23840 (of 66413): max relative diff=0.000045, 90.06 sec so far
Iteration 25165 (of 66413): max relative diff=0.000038, 95.06 sec so far
Iteration 26490 (of 66413): max relative diff=0.000032, 100.06 sec so far
Iteration 27817 (of 66413): max relative diff=0.000027, 105.06 sec so far
Iteration 29148 (of 66413): max relative diff=0.000022, 110.07 sec so far
Iteration 30473 (of 66413): max relative diff=0.000019, 115.07 sec so far
Iteration 31802 (of 66413): max relative diff=0.000016, 120.07 sec so far
Iteration 33125 (of 66413): max relative diff=0.000014, 125.07 sec so far
Iteration 34449 (of 66413): max relative diff=0.000013, 130.07 sec so far
Iteration 35773 (of 66413): max relative diff=0.000012, 135.08 sec so far
Iteration 37098 (of 66413): max relative diff=0.000011, 140.08 sec so far
Iteration 38411 (of 66413): max relative diff=0.000010, 145.08 sec so far
Iteration 39735 (of 66413): max relative diff=0.000010, 150.09 sec so far
Iteration 41059 (of 66413): max relative diff=0.000009, 155.09 sec so far
Iteration 42387 (of 66413): max relative diff=0.000009, 160.09 sec so far
Iteration 43709 (of 66413): max relative diff=0.000008, 165.09 sec so far
Iteration 45035 (of 66413): max relative diff=0.000008, 170.09 sec so far
Iteration 46356 (of 66413): max relative diff=0.000008, 175.10 sec so far
Iteration 47678 (of 66413): max relative diff=0.000008, 180.10 sec so far
Iteration 49006 (of 66413): max relative diff=0.000008, 185.11 sec so far
Iteration 50326 (of 66413): max relative diff=0.000008, 190.11 sec so far
Iteration 51649 (of 66413): max relative diff=0.000007, 195.11 sec so far
Iteration 52972 (of 66413): max relative diff=0.000007, 200.11 sec so far
Iteration 54294 (of 66413): max relative diff=0.000007, 205.12 sec so far
Iteration 55613 (of 66413): max relative diff=0.000006, 210.12 sec so far
Iteration 56941 (of 66413): max relative diff=0.000006, 215.12 sec so far
Iteration 58269 (of 66413): max relative diff=0.000006, 220.12 sec so far
Iteration 59595 (of 66413): max relative diff=0.000005, 225.13 sec so far
Iteration 60924 (of 66413): max relative diff=0.000005, 230.13 sec so far
Iteration 62247 (of 66413): max relative diff=0.000005, 235.13 sec so far
Iteration 63662 (of 66413): max relative diff=0.000004, 240.13 sec so far
Iteration 65098 (of 66413): max relative diff=0.000004, 245.14 sec so far
Iterative method: 66413 iterations in 251.36 seconds (average 0.003760, setup 1.64)
Value in the initial state: 48.49102760677303
Time for model checking: 251.354 seconds.
Result: 48.49102760677303 (value in the initial state)
Overall running time: 255.708 seconds.
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Note: There was 1 warning during computation.